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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3283fcd21547863478bff272ebb11c9c8d9e27382ab67979212e739ee8a4e36' 
  AND token = 'W71u1MAJ1V7w4kFmYnGrgpL4Uh2TDuyu1yuDIEt8WZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}